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Wood Breast Cell Model
The Wood cell model originates from an infiltrating ductal and lobular carcinoma of the breast.
Product Family: Wood Breast Cell Model
Disease Area: Cancer
Tissue Type: Breast
Clinical Diagnosis: Infiltrating ductal and lobular carcinoma of the breast
| Disease Area: | Cancer |
| Tissue Type: | Breast |
| Clinical Diagnosis: | Infiltrating ductal and lobular carcinoma of the breast |
| Age: | 65-69 |
| Sex: | Female |
| Ethnicity: | Caucasian |
| TNM Stage: | T2N0M0 |
| Grade: | IIA |
| Co-indications: | N/A |
| Medications: | Acetaminophen and Hydrocodone, Carvedilol, Omeprazole, Potassium Chloride, Metformin, Levothyroxine, Furosemide, Glipizide, Cyclobenzaprine |
| Country of Collection: | United States |
| Year of Origin: | 2013 |
Gene Mutations
| Gene | Alteration | Frequency (%) | Exon | Result |
| EGFR | E424Q | 8 | 11 | Mutated, Variant of Unknown Significance |
| MYC | Amplification | – | – | – |
Wood Growth Characteristics
The historical growth curve of Wood demonstrates consistent growth and highlights the lack of cell crisis.
STR Profile
AMEL: X
CSF1PO: 11, 13
D13S317: 9, 14
D16S539: 12, 13
D18S51: 13, 15
D21S11: 29, 31
D3S1358: 14, 18
D5S818: 11, 12
D7S820: 10, 11
D8S1179: 12, 13
FGA: 24, 26
Penta D: 11, 13
Penta E: 13, 14
TH01: 7, 9
TPOX: 9, 11
vWA: 18
Immunohistochemistry
Tumor sample diagnosis was confirmed by histology and immunohistochemical detection of tumor markers.
Lineage Markers
Immunofluorescence detection of lineage markers confirm epithelial phenotype using pan-keratin with DAPI overlay.
Tumorsphere Formation
Spontaneous formation of tumorspheres under low-attachment conditions.
ER-positive
Storage and Stability: Store frozen in liquid nitrogen.
Care and Use Instructions: See protocol for further details
Quality Control: All lots are tested for microbial and viral contamination, cell line cross-contamination, mycoplasma, and consistent growth capabilities. See Certificate of Analysis for further details.
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